This drug might increase the metabolism of estradiol when administered concurrently; patients on oral contraceptives are getting to be Expecting when concurrently treated with antiepileptic prescription drugs; advise an alternate contraceptive method to Gals getting this drug

pentobarbital will improve the level or outcome of clopidogrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

buprenorphine, lengthy-performing injection and pentobarbital both raise sedation. Prevent or Use Alternate Drug. Restrict use to individuals for whom alternate remedy options are inadequate

pentobarbital will reduce the level or impact of itraconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.

pentobarbital will minimize the level or influence of vincristine liposomal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unknown.

pentobarbital will decrease the level or impact of nateglinide by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Observe.

With therapeutic doses of TCAs, barbiturates raise metabolism and reduce blood concentrations of TCAs.

pentobarbital will lessen the level or outcome of gefitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

Drugs that involve prior authorization. This restriction needs that certain medical requirements be satisfied ahead of the acceptance with the prescription.

pentobarbital will lessen the extent or impact of lopinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

If inducer is discontinued, take into consideration oliceridine dosage reduction and monitor for indications of respiratory despair.

Monoamine oxidase inhibitors (MAOI) may possibly inhibit barbiturate metabolism and extend barbiturate results; monitor intently

pentobarbital will lessen the level or result of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

Reserve concomitant more info prescribing of those medications in patients for whom other cure alternatives are insufficient. Limit dosages and durations on the minimum essential. Monitor carefully for indications of respiratory despair and sedation.